Methylsulfonylmethane
Origin: Organic sulfur compound found naturally in fruits, vegetables, grains, animals and humans.
Dosage: Tablets, liquid, capsule or powder, topical and oral. Typically 1,000 mg to 3,000 mg daily with meals.
Claims: Reduces pain and inflammation.
What we know: MSM is an organic sulfur compound. Sulfur is needed to form connective tissue. MSM also seems to act as an analgesic by lessening nerve impulses that transmit pain.
Studies: A 2006 pilot study of 50 men and women with knee osteoarthritis showed that 6,000 mg of MSM improved symptoms of pain and physical function without major side effects. No large, well-controlled human studies have been performed.
MSM may cause stomach upset or diarrhea. Don’t use MSM if you are taking blood thinners.
I was told I needed a full knee replacement by one surgeon. I sought a second opinion and the second surgeon suggested that I first try a $20.00 set of heel wedges due to my alignment. I have bone on bone, but had immediate and noticeable relief. I later went ahead with orthotics from a cast prepared by a podiatrist as they are more permanent than the softer heel wedges. It has been two years since I have used the inserts as well as an injection of a synthetic fluid (Systnex?). My knee is better than it has been in over five years in respect to mobility and pain reduction. I hope you give the wedges a try; I wouldn't think they could hurt. I use the wedges for different shoes as the orthotics are fairly expensive. Hope this helps.