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Treatments > Drug Guide > Types of Drugs > Drug Guide: Osteoporosis Medications
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Drug Guide: Osteoporosis Medications

What do osteoporosis treatments do?

Osteoporosis medications (bisphosphonates included) can increase bone density and reduce the risk of fractures over time. Most osteoporosis drugs do this only by slowing bone loss: Bisphosphonates – alendronate (Fosamax), ibandronate (Boniva), risedronate (Actonel) and zoledronic acid (Reclast); the hormone calcitonin; the estrogens; and the selective estrogen receptor modulator raloxifene (Evista). Only one osteoporosis drug – teriparatide (Forteo) – also promotes bone growth.

How is osteoporosis connected to arthritis?

Osteoporosis is not a form of arthritis. Rather, it is a disease in which bones become brittle and weak, and eventually may break. Fractures, such as in the hips, often have long-lasting effects, including less mobility, decreased quality of life and increased depression. Like arthritis, osteoporosis can lead to disability. If bones are weak, the joints they form just don’t work well. In addition, the underlying processes involved in arthritis may contribute to osteoporosis.

Researchers have discovered that the chemicals involved in the inflammatory process, called cytokines, inhibit bone-building. And, in some cases, medications – especially corticosteroids – used to treat joint inflammation induce osteoporosis. Age also connects people with osteoporosis and OA, because both conditions tend to occur later in life.

When does a doctor prescribe osteoporosis medications?

Doctors look at several pieces of information before prescribing a bone-preserving or bone-building medication. A key piece of information is a patient’s bone mineral density. Bone density is determined by a quick and painless dual-energy X-ray absorptiometry (DEXA) scan of the hips, spine and wrists – the bones most likely to break due to osteoporosis. People should have a DEXA scan at age 65 and at a younger age if they take corticosteroids (such as prednisone) or have rheumatoid arthritis.

In people who do not have their bone mineral density tested, bones can weaken “silently,” and a fracture may be the first indication of osteoporosis that requires treatment. For those who have a DEXA scan, results are given as a Tscore, which compares the strength of a person’s bones with the peak bone mass of young adults. If bone density is normal, the Tscore will be at or above -1. A T score ranging from -1.1 to -2.4 indicates osteopenia, a preosteoporosis condition. Osteoporosis is diagnosed if the T score is -2.5 or lower.

The National Osteoporosis Foundation recommends starting treatment for people who’s T score is -2.0 or lower, or for those who have additional risk factors (such as taking a corticosteroid) and a T score lower than -1.5. For patients on bone medications, or for those who remain at risk for osteoporosis, bone density tests may need to be repeated every one to two years. When deciding whether it’s time to prescribe an osteoporosis medication, a doctor also considers a patient’s family history of osteoporosis: lifestyle (calcium intake, exercise, smoking, alcohol use); and other factors, such as age, gender, height and weight.

How fast can osteoporosis progress without medication?

Disease progression is determined by genetics, lifestyle and environmental influences. Adequate or inadequate amounts of calcium, vitamin D and weight-bearing exercise can influence the rate of bone deterioration. Without medication, however, bones that are already weak can continue to lose density at a rate of 1 percent to 5 percent per year.

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Teresa
07 Jul 2011, 07:37
I have been diagnosed with OA for about 4 years now i have it in my hands extremly bad as to where my hands are beginning to form knots on all mt joints and i have one finger that pops and sometimes difficult to open, my hips , my knees and shoulders. my doctor has me on tramadol it helps for the most part but, he refuse's to give me vicoden or any other pain medication when the pain gets really bad some times i can barely use my hands due to swelling or the pain, my hips pop when i walk and really hurt at night the only way i can sleep is on my back with a pillow under my legs.My ? is should i find another arthiritis Doctor. Thankyou Teresa
Cheryl
06 Jul 2011, 04:13
Dear Ellen I have had several back surgerys, I am fused from L4-S1. The doctor screwed up my surgery and part of it healed but part of it didn't. They can not fix it because the doctor put the rod through all 3 levels inside the bone. After this I have had trouble walking and when I would sit down my legs JUMP on there own. My pain doctor put me on medication for restless leg syndrome, it is also considered a drug to treat Parkinson's disease. If the first one your doctor gives you doesn't seem to work get him to give you another on because I had to try a few of them before I found one that worked for me. I don't know if you use a regular family doctor or a pain doctor but the pain doctor will prescribe it quicker than the family doctor.
Norm
26 Jun 2011, 09:27
I have arthritis in hips, neck and shoulders and just had Knee MCL surgery. Dr wants me to stop taking Prednisone and am down to 2mg now. Also have Crones and kidney disease so could not take more than Tylenol after surgery as anything upset my stomach. The doctors, for the Arthritis and Crones want me to take infusions of Remicade. Any comments good or bad would be welcome.
ermie dunson
16 Apr 2011, 03:08
I just found out I have lumbar arthritis...I take hydrocodone now...it seem's to keep me active...do I need to change...they are encouraging me to get the epidural shots..I'm not ready for that treatment yet...My pain seems to be ok with the meds i'm on now..keep's it to a dull pain v/s full blown all over body pain..should i change or use what is working for now! I don't want to move to fast! thank you, suzie dunson
cheryl murphy
18 Mar 2011, 19:41
I had Iron diffency Anemia in 2001 and a gastric bye pass in 2003. In 2001 my bone marrow was abnormal and they sent me to a Cancer Hosp. and I am being watched still. I take iron shots. Can RA show up in as being abnormal bonemarrow? These people have gone thue alot like myself. I guess I am not alone.
Dennis
07 Jul 2010, 13:27
I'v had severe Osteoporosis for about 6 months now and the pain was so bad that I thought I was going to end up in a mental institution.My Psychiatrist of all Doctors gave me a sample called Pennsaid and it is drops that you rub on the area. You need to try it!!
I'll tell you I Know what pain is I have (CRPS)or (RSD)
Dennis
Joyce C.
22 Jun 2010, 17:33
In response to Terri M. (March 13), I have several of your problems including kidney disease which leaves me without any arthritis medication except pain meds. I've had both hips replaced at 43 years old, back fusion (L4,5,S1), heart attack with 6 stents and severe artritis. I am now 51. And no, I am not obese or overweight. Does anyone know of an arthritis med that kidneys can tolerate? My pain is so severe and the hip replacements were failures. I can't even walk the length of a mall without having to sit down. Thanks- Joyce
doris rejino
03 Jun 2010, 23:22
i have pain in my back, both knees, elbows, and back of neck. when i go to the doctor, all i get are more pain pills. i want a better life. i am 65.ser
Maryann
03 Jun 2010, 20:57
Does anyone take Alendronate Sodium Tablets?

I have been on them for a few years and don't know if they really work. As I am not able to afford another bone density test at this time.

Just wondering if someone can tell me more about this tablet and if it has helped.

Thanks!

Maryann
Brenda
01 Jun 2010, 10:28
Terri

Try the forteo shots. Improved bone density immensely.
Brenda
01 Jun 2010, 10:24
Andrew

I took Forteo for 2 years. Cannot say I can tell a lot of difference in the pain, however, my bone density improved greatly. I would do it again if necessary. I was beginning to break bones on a regular basis, including both my femur bones. Bones are stronger, but still have pain. It could prevent another broken bone.
Alice
18 May 2010, 18:00
I have been on Forteo Shots for over a year now i for get to take them some times, just one more year to use it, then i go on a pill
I really dont see a way out of here.!!!!!!!!!!!!!!!!!!!!!
debbie
16 Mar 2010, 22:21
TO JOANNE- I have been on actional for over 15 yrs now. When I had a bone density done years age, my doctor told me that I actualy did build bone in my spine. So, it works. But if u have seen on yv lately, they say that some of these drugs can actually weeken bones after a long period of time. I have an appointment next month with my doc. If u send me an email, Makesure u put Joanne on it,so it doesnt go into span. good luck
Teri M
16 Mar 2010, 11:16
March 13, 2010

I 've had my right & left hip replacements done, the first was june 2008 the other sept. 2009 and a mild heart atack Dec. 2009.Besides I have arthritis which hurts my shoulders and back and sometimes my whole body. I've been taking toprol and crestor to prevent another heartatack. I do wonder if I really need this? also I take prednisone 4mg for my arthritis and will taper down. I also take ecotrin and synthroid along with omeprazole 20mg. I just wonder if Im wasting my time with all these pills. I also take over the counter, caltrate and D sometimes. The trouble is I am still hurting. I walk with some pain and can't walk as long as before. I am also doing water arobicks twice a week and one day of strenthing along with some walking when the weather is good. I stretch at home. I still don't get any answer. I will be seeing my doctor tomorrow regarding the density test I took and was told I have osteoporosis. Also my test for pereforal arthritis is was ok. What kind of medication do you think they will priscribe for this. I'm only a young 75 and I want to get back to where I was in life. Do you have
ethel silverstein
19 Jan 2010, 19:56
I was diagnoised with Fibromylgia maybe 6 years ago. I get a lot of pain that before that time the doctor did not want to answer.
My current doctor does not think there is such a thing and perhaps making things up and thinks I have mental problem. I have Osteoporis,and have hd a broken hip and a number of other breaks. Osteoarthritis, Bladder, Stomach, Vertigo, Migrains and Arthritis all over. Try and make all that up and he does not believe there is such a thing. I live with all of this and many persons cannot not All these things that I have to ingest does not help the bones, neither do the shots help. What do I tell my doctor as he refuses to read about it. I like this person but not on this. HELP
joanne
18 Jan 2010, 15:30
I have been taking Actonel I have been doing well however, I am wondering if there are others out there on this drug,and how are you doing? Have you noticed a change and how long did your Dr.tell you that you would take this drug? Thanks Joanne
Joyce
07 Dec 2009, 17:22
After complaining of pains in both arms down to my hands during the nighttime while I'm sleeping, I had some tests done, and I have been diagnosed with Arthritis of the spine and neck.My Rheumatologist has prescribed Boniva and Prednisone. Are these medical choices right for me?
I am also going for Physical Therapy on my arms and neck twice a week.
Is there any other advice you can give to help relieve the pain.

Thank you- Joyce
ANDREW KROESCH
01 Dec 2009, 20:07
Could any give me more information on Forteo. I have been taking it for 5 mths, an have not seen any change nor feelings. My pain is just as bad, Im 55 yrs old an some what lost. My pain managment can really offer no help on my question. Thank you-Andrew.
gloria katz
15 Sep 2009, 17:25
sirs
i have ostoporios and i am given by my doctor the drug bonivia iv every 3 months do you think i would be a person to get the new drug denosumab ?would i still take bonivia plus this new drug? i have not had any breaks of my bones but acording to my cat scans i have a grade 4 condition Do you think this new medication would help me?
sincerly yours gloria katz
ella joyner
19 Aug 2009, 22:42
I have had a back operation L5,4,and 3. I hurt and my toes are numb and my feet and the legs. I can walk and they do not hurt as bad , I sit down or lay down I have cramps. I go to my Dr. but I need something for more relief. I would like to know why my legs are so bad , I need to know what to do, Thanks Ella Joyner
Patty
08 Jul 2009, 11:25
I have been on Methotrexate for 6 years due to RA. When diagnosed with osteoporosis, I started taking Forteo. I had to stop Forteo after 2 months of severe pain. During that time RA really took over, metho was ineffective and is having a tough time regaining control. I am not able to take any of the infusion drugs so am hoping that metho will persevere. I am sending this as I found very little info on the internet re: the combination of these two drugs.
Thanks, Patty
Jo-Ann Boyd
05 Jun 2009, 15:51
My Vit.D was 17 and I too had fractures from simple tasks. You must build up your Vit.D level with avengence.
I take caltrate with 600mg calcium plus 400 ml Vit D three times a day. If you count up what you get in food you will find your diet is lacking, I am sure. Milk is a fortified food.
Be sure to get sunshine. I go out without sun screen for 15 min.early in the am before the sun gets hot.
I felt much better and had less leg pain within a very short time and my Vit D level is back to normal .
Hope this is helpful. Jo-Ann Boyd
Terri Mauro
14 May 2009, 15:56
I am trying to find some information on severe bone loss. I have had many fractures.
I am trying to heal from pelvic fractures
and sacrum fracture. My rheumatologist said
my serum Vit. D is 22. I am having a hard time finding a way to replace the vit. d.

I am allergic to yellow food and drug coloring, and seafood. Because of this I have
not found a po med I can take. Any help you
can send my way would be a miracle.

Thank you-Terri

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