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Symptoms > Inflammation > Inflammation and Heart Disease
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Inflammation and Heart Disease

By Roxanne Nelson and Donna Rae Siegfried

You’ve heard it before: “Watch your cholesterol and keep an eye on your blood pressure.” Although everyone should aim for a cholesterol level below 200 and a blood pressure reading in the normal range, it is especially important for those with inflammatory or autoimmune conditions, such as RA and lupus. 

Mounting evidence points to an inflammation-heart disease connection; inflammation contributes to the development of heart disease by making the inner lining of arteries swell, narrowing the opening through which blood can flow. Narrowed arteries increase blood pressure (hypertension) and up the risk of heart attack and stroke. Cholesterol – a component of the sticky fat- and debris-filled substance called plaque – further narrows arteries by clogging them with gunk.

Arthritis Foundation-funded researcher Daniel Solomon, MD, and colleagues at Brigham and Women’s Hospital in Boston, found that women with RA are twice as likely to have heart attacks as those who don’t have the disease. Another inflammation-blood pressure study indicates that a person’s current level of C-reactive protein (CRP) – a key player in inflammation – can indicate future high blood pressure development. In fact, the study’s researchers suggest high blood pressure may be an inflammatory disorder.

If your blood pressure is around 140/90, you might think you’re OK. But recently changed guidelines state that people who have prehypertension – that is, systolic (top number) pressure of 120 to 139 and diastolic (bottom number) pressure of 80 to 89 – are at high risk of developing high blood pressure and should make lifestyle changes, such as quitting smoking, exercising more and losing excess weight.

And what about those cholesterol numbers? Measuring a person’s total cholesterol can be misleading. A more accurate test is one that measures the various components of the total cholesterol level. Cholesterol is carried through the body by lipoproteins, of which there are two basic types: high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). HDLs are the “good” type; they deposit excess cholesterol in the liver, where it is then metabolized out of the body. LDLs are the “bad” kind; they deposit cholesterol into the arteries.

Experts agree that the LDL level should be kept as low as possible. The standard target has been 100 mg/dL of LDL, but a recent study found significant benefit from driving LDL down into the 60s. HDL should be as high as possible. An HDL level below 40 mg/dL is considered a major risk factor for developing heart disease, so aim for an HDL level higher than 40 mg/dL.

Liz
23 Jul 2010, 19:13
I read through all your comments and I feel for you. I used to suffer a lot from my RA (as well as IBS, asthma and allergies) but I've been symptom free for 4 years since I did an anti-inflammatory diet program (From the book "The Guts and Glory Program: Restoring Your Digestive Health" by Brasco and Rubin).

I highly recommend this program for anyone suffering from autoimmune diseases.

I recently was diagnosed with high blood pressure and my RA symptoms were starting to come back. I am doing the protocol again and my blood pressure has come down and the RA seems to be in remission again.
Carlena Lawrence
28 Apr 2010, 03:47
I've been having trouble with my left shoulder,left hand both knees,now my eyes,ears,head and nose I was told 20yrs. ago I had Arthritis in my knees now the doctors say its in all parts of my body i went to an Specialt today he gave me two shots in my knees and patches for my shoulders which is(Flector) and he had (Steriod)in the shots and it has made me sick my head has been stobbing since 4:00 p.m its now 4:43 in the morning and it have not stop ,Icalled his answer services and explained to him twice he said he didn't understand it but I've taken shots before and never got this pain.What you think is wrong?
Lisa
02 Mar 2010, 22:02
I have been on methotrexate since June last year and had one shot of Humira--got super sick after that first injection. I have made diet changes and FEEL GREAT, but just got results back and my blood scores are high in many places (WBC, platelets, CRP). Does anyone have any thoughts on this? Why would my scores be high, but my comfort AWESOME? Please advise.
Mary
15 Feb 2010, 19:10
What condition would cause excruciating pain in my hands; seems to be worsened by cold air exposure; also have experienced a terrible pulling - almost like a tendon is being ripped - that runs from base of middle f Thanks.inger through palm to wrist - really painful. Anyone have any ideas?
Ann
01 Feb 2010, 09:08
I have been suffering for years with cold numbness with my hands , my nuckles hurt and gets red...is there any thing I can use to get the swollen down and the numbness to disapear?
thank you, Ann
caro
03 Jan 2010, 09:18
I have extreme pain in my hands especially in my left hand. Can't hold hand up to talk on phone, like it goes to sleepand wake up with pins sticking in it. Holding it down gets more relief. Sews alot and be pulling on fabric. This is my source of income, is there anything I can do I take ibuprofen but pain wake me in the night like a toothache
thanks
Rosemary
08 Oct 2009, 12:46
To Sharon (9-28-09) I have been seeing a
Rheumatologist for approximately 10yrs+. I had the same symptoms you described which my physician explained as a problem with the Sciatic nerve in my back. There is much information on the net regarding the sciatica and various treatments and/or tests.(www.MedicineNet.com & www.Medlineplus)
My physician referred me to Physical Therapy which consisted of Acquatic therapy (make sure any exercises ordered are ordered to be done in a swimming pool--(my Aunt was referred for these same symptoms by a different physician; however her exercises were ordered to be done outside a pool which made her pain worse.)
After the swimming
exercises I had an Ultra sound massage applied directly to the affected areas.(Here again my poor Aunt's physician ordered her massage to be done manually by hand causing her so much more extreme pain she was never able to finish her treatments.)
After my Ultra sound treatment, a Tens unit was applied to my lower back in areas that I was having pain in. Then hot packs were placed over the leads that are attached to the unit for a specified time. I received these treatments twice weekly for a total of approximately nine treatments.
Hopefully I have not confused you. My treatment basically consisted of:
l. Exercises in warm pool
2. Ultra sound massage
3. Tens unit application with hot packs
This completely solved my problem, my insurance covered it, and I have not had to repeat this therapy.
Hopefully this could help you out.
Good luck.

sharon
28 Sep 2009, 19:26
i have been getting alot of pain in my leg. starting from my buttock going all the way to my foot. Dr. says it is arthritis and there is nothing he can do for me.

can you please suggest anything to me so i can get some relief. it is so hard for me to sit

Sharon
Margaret Conzulo
22 Jul 2009, 12:05
I am experiencing pain on the left side of my neck, shoulder and down my arm. Mostly what triggers the pain in cold air. I was diagnosised with arthritis 1 1/2 yrs ago, and it seems to be getting progressively worse, is the sensitivity to cold normal for this condition? This is driving me crazy, I am wearing winter clothes in Texas heat.
debbi
14 May 2009, 05:19
In regards to Rosemary's comment/question....a friend of mine who had kind of big/swollen calves (long term) which were very sensitive to touch was diagnosed with a kidney problem. Once her kidneys worked better her calves became less sensitive. She had some type of Nephropathy.She now often wears compression stockings but also because she got a DVT which went to her lungs and she was forunate to come out alive. I put my feet and legs up and also ice when needed. It helps.
ROSEMARY MELENDREZ
29 Apr 2009, 02:36
MY CALVES ESPECIALLY MY RIGHT LEG CALF ARE SO SENSITIVE THAT I CAN'T STAND ANY PRESSURE ON THEM. IF A SIT FOR A WHILE THR SAME RIGHT LEG STARTS SWELLING FROM THE FOOT TO THE CALF. THIS ALL MAKES ME WORRY AND THAT TIRES ME OUT. IT'S CONSTANT PAIN WHEN I REST MY LEGS FLAT. THANKS FOR ANY INSIGHT TOWARD HELPING ME IN THIS MATTER. THANK YOU IN ADVANCE FOR A REPLY.
melissa george
19 Apr 2009, 12:30
i constantly haveing pains from my back to my neck ,my eyes hurt my purls so beating and i feel tickles like some one pass a hair or something on my face.its really hard to explain my heart go beating hard it would just stay and bond. i cant hear no sad news and i would like to no why.
kathie javellana
07 Apr 2009, 18:16
I have been having pain from my shoulder to my elbows. Feels like muscles getting tight. cant fasten my bra without pain, sudden movements to reach something high, or in what were normal directions now give me excruciating pain somewhat like an electrical feeling going through the arm.

what could this be? thank you for your reply.

kathie

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