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Symptoms > Inflammation > Inflammation and Heart Disease
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Inflammation and Heart Disease

By Roxanne Nelson and Donna Rae Siegfried

You’ve heard it before: “Watch your cholesterol and keep an eye on your blood pressure.” Although everyone should aim for a cholesterol level below 200 and a blood pressure reading in the normal range, it is especially important for those with inflammatory or autoimmune conditions, such as RA and lupus. 

Mounting evidence points to an inflammation-heart disease connection; inflammation contributes to the development of heart disease by making the inner lining of arteries swell, narrowing the opening through which blood can flow. Narrowed arteries increase blood pressure (hypertension) and up the risk of heart attack and stroke. Cholesterol – a component of the sticky fat- and debris-filled substance called plaque – further narrows arteries by clogging them with gunk.

Arthritis Foundation-funded researcher Daniel Solomon, MD, and colleagues at Brigham and Women’s Hospital in Boston, found that women with RA are twice as likely to have heart attacks as those who don’t have the disease. Another inflammation-blood pressure study indicates that a person’s current level of C-reactive protein (CRP) – a key player in inflammation – can indicate future high blood pressure development. In fact, the study’s researchers suggest high blood pressure may be an inflammatory disorder.

If your blood pressure is around 140/90, you might think you’re OK. But recently changed guidelines state that people who have prehypertension – that is, systolic (top number) pressure of 120 to 139 and diastolic (bottom number) pressure of 80 to 89 – are at high risk of developing high blood pressure and should make lifestyle changes, such as quitting smoking, exercising more and losing excess weight.

And what about those cholesterol numbers? Measuring a person’s total cholesterol can be misleading. A more accurate test is one that measures the various components of the total cholesterol level. Cholesterol is carried through the body by lipoproteins, of which there are two basic types: high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). HDLs are the “good” type; they deposit excess cholesterol in the liver, where it is then metabolized out of the body. LDLs are the “bad” kind; they deposit cholesterol into the arteries.

Experts agree that the LDL level should be kept as low as possible. The standard target has been 100 mg/dL of LDL, but a recent study found significant benefit from driving LDL down into the 60s. HDL should be as high as possible. An HDL level below 40 mg/dL is considered a major risk factor for developing heart disease, so aim for an HDL level higher than 40 mg/dL.

Rosemary
08 Oct 2009, 12:46
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To Sharon (9-28-09) I have been seeing a
Rheumatologist for approximately 10yrs+. I had the same symptoms you described which my physician explained as a problem with the Sciatic nerve in my back. There is much information on the net regarding the sciatica and various treatments and/or tests.(www.MedicineNet.com & www.Medlineplus)
My physician referred me to Physical Therapy which consisted of Acquatic therapy (make sure any exercises ordered are ordered to be done in a swimming pool--(my Aunt was referred for these same symptoms by a different physician; however her exercises were ordered to be done outside a pool which made her pain worse.)
After the swimming
exercises I had an Ultra sound massage applied directly to the affected areas.(Here again my poor Aunt's physician ordered her massage to be done manually by hand causing her so much more extreme pain she was never able to finish her treatments.)
After my Ultra sound treatment, a Tens unit was applied to my lower back in areas that I was having pain in. Then hot packs were placed over the leads that are attached to the unit for a specified time. I received these treatments twice weekly for a total of approximately nine treatments.
Hopefully I have not confused you. My treatment basically consisted of:
l. Exercises in warm pool
2. Ultra sound massage
3. Tens unit application with hot packs
This completely solved my problem, my insurance covered it, and I have not had to repeat this therapy.
Hopefully this could help you out.
Good luck.

sharon
28 Sep 2009, 19:26
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i have been getting alot of pain in my leg. starting from my buttock going all the way to my foot. Dr. says it is arthritis and there is nothing he can do for me.

can you please suggest anything to me so i can get some relief. it is so hard for me to sit

Sharon
Margaret Conzulo
22 Jul 2009, 12:05
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I am experiencing pain on the left side of my neck, shoulder and down my arm. Mostly what triggers the pain in cold air. I was diagnosised with arthritis 1 1/2 yrs ago, and it seems to be getting progressively worse, is the sensitivity to cold normal for this condition? This is driving me crazy, I am wearing winter clothes in Texas heat.
debbi
14 May 2009, 05:19
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In regards to Rosemary's comment/question....a friend of mine who had kind of big/swollen calves (long term) which were very sensitive to touch was diagnosed with a kidney problem. Once her kidneys worked better her calves became less sensitive. She had some type of Nephropathy.She now often wears compression stockings but also because she got a DVT which went to her lungs and she was forunate to come out alive. I put my feet and legs up and also ice when needed. It helps.
ROSEMARY MELENDREZ
29 Apr 2009, 02:36
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MY CALVES ESPECIALLY MY RIGHT LEG CALF ARE SO SENSITIVE THAT I CAN'T STAND ANY PRESSURE ON THEM. IF A SIT FOR A WHILE THR SAME RIGHT LEG STARTS SWELLING FROM THE FOOT TO THE CALF. THIS ALL MAKES ME WORRY AND THAT TIRES ME OUT. IT'S CONSTANT PAIN WHEN I REST MY LEGS FLAT. THANKS FOR ANY INSIGHT TOWARD HELPING ME IN THIS MATTER. THANK YOU IN ADVANCE FOR A REPLY.
melissa george
19 Apr 2009, 12:30
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i constantly haveing pains from my back to my neck ,my eyes hurt my purls so beating and i feel tickles like some one pass a hair or something on my face.its really hard to explain my heart go beating hard it would just stay and bond. i cant hear no sad news and i would like to no why.
kathie javellana
07 Apr 2009, 18:16
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I have been having pain from my shoulder to my elbows. Feels like muscles getting tight. cant fasten my bra without pain, sudden movements to reach something high, or in what were normal directions now give me excruciating pain somewhat like an electrical feeling going through the arm.

what could this be? thank you for your reply.

kathie

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