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News > Study Shows Vitamin D Doesn't Help Knee Osteoarthritis
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Study Shows Vitamin D Doesn’t Help Knee Osteoarthritis

A new study finds this supplement won’t improve pain or keep the disease from getting worse, but doctors emphasize its role in bone health.

By Jennifer Davis

11/16/10 Taking daily vitamin D supplements does not reduce the pain of knee osteoarthritis, or OA, and it does not slow the disease’s progression, according to a study presented last week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

“I think there’s a high level of enthusiasm for vitamin D currently. People think it will help in many medical areas,” says lead investigator Timothy McAlindon, MD, a professor of medicine in the division of rheumatology at Tufts New England Medical Center in Boston.

However, when it comes to the vitamin’s effect on knee OA, the recent findings are “not what we had hoped to have seen,” Dr. McAlindon says.

OA, the most common form of arthritis, is marked by the degeneration of cartilage in and around joints, which causes pain that can severely limit people’s mobility.

Vitamin D is needed to properly absorb calcium. If you aren’t getting enough of it – by absorbing it through sunlight, taking supplements or getting it from foods like oily fish, fortified milk, eggs and cheese – your bones can become weak and fracture. Some earlier studies have indicated that vitamin D helps slow the progression of knee OA, but those findings weren’t supported in this latest study conducted by researchers at Tufts New England Medical Center.

“There have been some observational studies looking at vitamin D levels and knee OA. At the time we started this study there were only one or two and they were positive. During the course of our study, others came out that were more negative,” Dr. McAlindon says. “My assumption was that [vitamin D] would work, but the body of evidence changed from being positive to more negative.”

Dr. McAlindon and his research team studied 146 people – mostly white women, with an average age of 62 – who had symptomatic and radiographic knee OA. Researchers split participants into two groups. One group took vitamin D every day, starting with a dose of 2,000 IU, which was increased as needed for patients to reach levels of 30 ng/ml or higher. The other group took a placebo. For all participants, researchers measured pain, physical function, damage visible through X-rays and damage visible on MRIs at the start of the study and one year later.

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Gayle
14 Jan 2011, 09:22
WE just began taking Vit D with Calcium.. been on Boniva for 3 yrs. Both my husband and I have arthritis and it has progressed ... we are trying this hoping to avoid surgery... age 80 and 81..
It's worth the try.. will let you know in
4 mos.. Measuring pain and ability to move more easily...
omar
21 Dec 2010, 03:13
http://www.mskreport.com/articles.cfm?articleID=3232
Henry Lahore
17 Nov 2010, 08:24
Agreed. The benefits of vitamin D do not start until 40ng/ml. See the chart at VitaminDWiki.com
CLS
17 Nov 2010, 00:10
30 ng/ml, 25 OH D, is not sufficient nor reflective of a natural, healthy, normal level of vitamin D.

The optimal range of vitamin D is 50-80 ng/ml, which is key to achieving repletion.

The results of this study are of little value when considering vitamin D supplementation to treat the disease.

Since raising my serum level of circualting vitamin D to 70 ng/ml, my arthritis and joint pain has vanished completely, for 3 years running.

Vitamin D is the only supplement I take. To be clear, I do not take anyhting else, including aspirin.

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