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Conditions > Other Conditions > More Conditions > Changing Cholesterol Levels
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Changing Cholesterol Levels

By Brenda Goodman

Having a “normal” LDL cholesterol level may not protect you from a heart attack.

That’s the message of a new national study that looked at more than 136,000 patients admitted to hospitals for heart attacks from 2000 to 2006.

The surprise? Nearly three-quarters of them had low-density lipoprotein (LDL) cholesterol levels lower than 130 mg/dL, a level considered to be normal for anyone without a history of heart disease or diabetes under current government guidelines.

What’s more, half of the heart attack patients in the study had LDL cholesterol levels under 100, a number currently considered to be optimal for most people.

“I think what this illustrates is that the thresholds in the guidelines may need to be reconsidered,” says Gregg C. Fonarow, MD, a cardiologist at Ronald Reagan UCLA Medical Center in Los Angeles and lead author of the study, which was published in the January issue of the American Heart Journal.

Dr. Fonarow says the risk for cardiovascular events in the study appeared to be low for LDL levels below 60 mg/dL.

Those numbers, while difficult to obtain, are good targets for people who have other risk factors for cardiovascular disease like a history of smoking, diabetes, or people with inflammatory conditions like rheumatoid arthritis.

John Hall
20 Apr 2009, 15:46
Maybe this study indicates that something other than LDL would be a better risk factor. What is shown in the article tells me that more people with an LDL under 100 have heart attacks than those with an LDL over 130, i.e. that higher not lower is better. Obviously this conclusion is based on what little information is provided in the article and not on what encompasses the entire study.

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