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Conditions > Osteoarthritis > Osteoarthritis Treatment > Osteoarthritis Medications
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Osteoarthritis Medications

What medications are used to treat osteoarthritis?

There are no medications yet that treat the underlying disease process. Instead, the goal of medical treatment for osteoarthritis (OA) is to reduce pain and stiffness and make it easier to remain active.

The most commonly used medications for osteoarthritis are:

Analgesics – Analgesics are drugs that relieve pain. These medicines do not reduce inflammation or swelling. But if pain relief is your main concern, these drugs tend to have fewer side effects than drugs that reduce inflammation.

The most commonly used analgesic is acetaminophen, which the American College of Rheumatology recommends for the treatment of mild or moderate pain caused by osteoarthritis. Acetaminophen is available over the counter as generic and store brands or the name brand Tylenol, Anacin (aspirin-free), Excedrin caplets and Panadol. Acetaminophen can be taken in doses of 325 to 1,000 mg every four to six hours, but no more than 4,000 mg should be taken per day. This drug can interact with alcohol. Check with your doctor before using acetaminophen if you consume more than three alcoholic drinks per day.

If you have severe pain, your doctor may prescribe a stronger analgesic. Examples include propoxyphene hydrochloride (Darvon, PC-Cap and Wygesic), acetaminophen with codeine and tramadol (Ultram). Often, these drugs are used only for short periods because the carry the risk of dependence.

Topical analgesics – These are creams, rubs and salves that are applied directly to the painful area.  One of them, Voltaren Gel, is a topical formulation of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac, and is available only by prescription. The rest are available over the counter. Their effects come from one or more of a variety of active ingredients. The most common ingredients are:

Capsaicin – A highly purified natural ingredient found in cayenne peppers, capsaicin works by depleting the amount of a neurotransmitter called substance P that is believed to send pain messages to the brain. For the first couple of weeks of use, the ingredient may cause burning or stinging. Capsaicin is available under the product names Zostrix, Zostrix HP, Capzasin-P and others. Menthacin includes both capsaicin and counterirritants.

Counterirritants – Like stepping on your toe to take your mind off a headache, counter-irritants stimulate or irritate the nerve endings to distract the brain’s attention from musculoskeletal pain. Counterirritants encompass such substances as menthol, oil of wintergreen, camphor, eucalyptus oil, turpentine oil, dihydrochloride and methlnicotinate and are found in products such as ArthriCare, Eucalyptamint, Icy Hot and Therapeutic Mineral Ice.

Salicylates – Like the salicylates found in many oral pain relievers, these compounds may work by inhibiting prostaglandins. They primarily work topically as counterirritants, themselves stimulating or irritating nerve endings. Brand name examples of topical analgesics containing salicylates include Aspercreme, Ben-Gay, Flexall, Mobisyl and Sportscreme

 

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George Marker
16 May 2012, 13:59
I am 75 years old and I have been dealing with severe lower back pain for the past two years. I first went to a Chiropractor and after numerous visits I do not see any permanent relief so I next tried a specialist. I had numerous xrays of my lower and upper back and my hip. The results that I had arthritis in my upper and lower back and a small amount in my hip. My specialist told me that I should learn to live with the pain. That was unacceptable so I have had shots in lower back with two different pain clinics, the only difference was in the method of application. The next thing that was recommended was implants along the spine called x-stops which are supposed to maintain the gaps between the vertebrates. Net result no impact.

As a last resort I was given the option of becoming addicted to narcotic drugs or live with the pain. So far I have chosen to live with the pain. In the meantime the pain in my hip is getting worse and sooner or later, I will have to do something about this issue.
In the meantime, I am living with the pain and trying to be very careful with the amount of physical activity that I try to handle. If the pain becomes too intense, I stop what I am doing until the pain subsides, then I get back at the chore at hand. It takes me a lot longer to accomplish many tasks but I have nothing but time.

I have to been careful with the types of drugs that I take because I only have one kidney. The lost to other in bout with cancer. Thank god, I survived that ordeal
Christa Cohen
15 May 2012, 18:20
I'm reading all these blogs and the suffering and can't help wondering why we can walk on the moon and not find a single pain medication that does not kill the heart, the kidneys, or the liver?
My arthritis started with inflammation, which I ignored, because I thought there is no heart,liver, kidney or anything important in my bud which could get ruined, but I forgot about the joints. Well the inflammation killed the cartilage.
The lesson I learned is not to ignore "inflammation!".
Then I was shocked to find out that no one can help me, not even doctors, except myself. And then I became health conscious. The lesson I learned is prevention! Anti-Oxidants!!!
I discovered L-Glutathione Reduced, Setria by Healthy Origins. I also recommend "Amrit Kalash, Ambrosia" from the Maharishi Ayurveda. I realize now that it's those radicals that do us all in, except those fortunate few who genetically inherited the capacity for their bodies to make their own anti-oxidants into advanced old age, that is why old age runs in families. Well, I am now taking in Anti-oxidants from the outside to make sure that I have them. We all need them!
Christa Cohen
15 May 2012, 16:29
I have Osteo-arthritis of the right hip area. Since I want to get very old, I do not want some body replacement in me, that has to be replaced in 15 years. I am waiting for stem cells to give me my own new hip.
In the meantime I'm trying to find a cure for Arthritis. So far I have tried every supplement for Arthritis on the Internet, and the best things I found so far have been SAMe, and 10% DMSO solution from Dr. Jacob's lab for sensitive skin. ASU is supposed to repair cartilage, so is SAMe, and Glucosamine Sulfate (not HDL). The very best Exercise I found is the DVD "Dr. Lam's TAI CHI for Arthritis", it's even better than swimming, which I also do about 15 hrs a week in my heated pool. I know that the cure is out there, we just have not found it yet!
Linda
01 May 2012, 09:45
Ann, I'm sorry you are so uncomfortable, I am 48 and DREAD the thought of how badly I will hurt when I'm 50-55, if I am just about incapacitated now a good portion of the time. I can go along and be fine, as long as I do NOTHING, no quality of life, no enjoyment in anything. Then I onlyhave to deal with the stiffness, but if I do my nornal everyday things, my body feels as if I've run a marathon and been hit by a truck. My Dr. does not listen and the orthopedist is a Joke with the PT recommendations,which means sit in a chair with a hot rag on an excersize ball for 20 mins... tht's it.
ann davey
22 Mar 2012, 14:05
i am 48 and im on nortrypltline , and i take glucosamine with condrtion every day, i have had a mri but just the top half of me and they say i have osteoartheritis, but my calfs ache a lot, and my right shoulder, but not my fingers, just every day things like drying my hair and straightning it, really aches, even if i have to scrub a pan, i feel like ive done ironging all day, but i havent, i have a shitsu chair as well, not sure if i should be going back to me doctors, or just plod along????
cathie
08 Sep 2011, 18:24
I also have degenertive disc and the same for my osteoarthritis. I applied for ssa disibility back in Feb 2010 was accepted in April 2010. It was not hard just filled in out on line, I gave them all fo my Drs names phone # and fax...they retrieved all the info they needed was very easy
Debbie
30 Jul 2011, 13:50
Barbara Wolfe, I have both conditions along with a myriad of other problems but, I have had one back surgery to remove a herniated disc in 1997 and most recently a double fusion of L-5 S1 in Sept.,2010. I applied for disability in Nov., 2010 and was awarded disability in Feb., 2011, pretty fast, and I wasn't required to wait the normal 5 month period after being notified. When you do the form online you'll need as much of your medical history as possible which may mean going to your doctor(s) and requesting a copy of your records which you can then take in to the SS worker intially assigned to your case once you have finished the application. They will scan it in and it should speed up the process. Be sure to note that you need them returned to you. It doesn't matter how thick your records are the more you have documenting your physical problems the better. Also, do not leave anything blank on your application. You can always write I don't know or I don't recall. Best Wishes and Gods Speed to you!
BARBARA WOLFE
20 Jul 2011, 16:21
has anyone heard of anybody getting disablality for denerative disc disease,denerative osteoarthritis? and bulging disc?
Cheryl Van Cleave
22 Jun 2011, 08:30
Most of everything I read about arthritis is about knee & hip pain. I have arthritis in my neck, shoulders, arms, hands, & fingers. Isn't there anything that will help me. Surgery or meds. I can't sleep lie down or sit. What am I supposed to do?
Patty A Owens
02 May 2011, 06:41
Hello. I am 47 and have had orthopedic issues all my life. I worked from the time I was 14 until I was 43, when I injured my back while moving. I was diagnosed with degenerative disc disease and degenerative joint disease 16 years ago. In Delaware, I had Medicaid, several doctors and a workable medication regimen. Since moving to Florida, I have been refused Medicaid, have no insurance or reliable source of income and therefore, must pay for my doctor and all medications out of pocket. As I am drug sensitive to the usual treatments, it was difficult to come up with a workable program in Delaware, but we did. Now, because I moved to Florida, so many medications are restricted and I was denied disability, I live in pain and can only sit in my recliner, where I also sleep and wait for any kind of relief. I am lacking specialists and physical therapy as well. It is difficult to prove disability when you can not afford doctors and tests. As this has been going on for so long and now my C spine is narrowing, and other facets are incurring more damage. I wonder if I am correctly diagnosed. Are there any research, as in free, programs, in Florida, for diagnosis or treatment?
Bonnie Ramsey
09 Apr 2011, 07:26
Lorraine Mueller asked about her hands getting very cold. Ask your doctor, cardiologist or rheumatologist about Reynaud's syndrome. It cause constriction of the peripheral blood vessels. Low doses of vasodialaters (medications that cause the blood vessels to relax/expand, such as Procardia, can help. Submerging your hands in warm, not hot, water for a few minutes also helps.

Reynaud's can also cause severe muscle pain in cold weather. The pain may be diagnosed as a generic arthralgia. Treatment for the root cause can dramatically reduce pain levels and make winter much more enjoyable.

Been there. Still there, but with much less pain. I hope you find relief soon.
Lorraine Mueller
07 Apr 2011, 15:45
I was told that the reason my hands get so cold is due to not enough fat on my body & not due to OA. My hands feel like ice & get stiif. It takes awhile before they warm up again. It happens quite often through out the day. Any suggestions why this happens.
Alice Ramirez
01 Mar 2011, 15:52
For severe, crippling, painful arthritis in the hips, I can enthusiastically recommend the surgery option mentioned at the end of page 3. I was so afflicted with osteoarthritis that I could barely shuffle from one end of my house to the other. A few months after my second hip replacement surgery, I could wear high heels again, although I mostly stick to 2" heels and never go above 3" heels. It is wonderful! I feel 20 years younger. Every time I shove my feet into high heels, I feel as if I am flipping the bird at arthritis. It is WONDERFUL!

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