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Conditions > Osteoarthritis > All About Osteoarthritis > Osteoarthritis Treatment
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Osteoarthritis Treatment

What medications are used to treat osteoarthritis?

There are no medications yet that treat the underlying disease process. Instead, the goal of medical treatment for osteoarthritis (OA) is to reduce pain and stiffness and make it easier to remain active.

The most commonly used medications for osteoarthritis are:

Analgesics – Analgesics are drugs that relieve pain. These medicines do not reduce inflammation or swelling. But if pain relief is your main concern, these drugs tend to have fewer side effects than drugs that reduce inflammation.

The most commonly used analgesic is acetaminophen, which the American College of Rheumatology recommends for the treatment of mild or moderate pain caused by osteoarthritis. Acetaminophen is available over the counter as generic and store brands or the name brand Tylenol, Anacin (aspirin-free), Excedrin caplets and Panadol. Acetaminophen can be taken in doses of 325 to 1,000 mg every four to six hours, but no more than 4,000 mg should be taken per day. This drug can interact with alcohol. Check with your doctor before using acetaminophen if you consume more than three alcoholic drinks per day.

If you have severe pain, your doctor may prescribe a stronger analgesic. Examples include propoxyphene hydrochloride (Darvon, PC-Cap and Wygesic), acetaminophen with codeine and tramadol (Ultram). Often, these drugs are used only for short periods because the carry the risk of dependence.

Topical analgesics – These are creams, rubs and salves that are applied directly to the painful area.  One of them, Voltaren Gel, is a topical formulation of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac, and is available only by prescription. The rest are available over the counter. Their effects come from one or more of a variety of active ingredients. The most common ingredients are:

Capsaicin – A highly purified natural ingredient found in cayenne peppers, capsaicin works by depleting the amount of a neurotransmitter called substance P that is believed to send pain messages to the brain. For the first couple of weeks of use, the ingredient may cause burning or stinging. Capsaicin is available under the product names Zostrix, Zostrix HP, Capzasin-P and others. Menthacin includes both capsaicin and counterirritants.

Counterirritants – Like stepping on your toe to take your mind off a headache, counter-irritants stimulate or irritate the nerve endings to distract the brain’s attention from musculoskeletal pain. Counterirritants encompass such substances as menthol, oil of wintergreen, camphor, eucalyptus oil, turpentine oil, dihydrochloride and methlnicotinate and are found in products such as ArthriCare, Eucalyptamint, Icy Hot and Therapeutic Mineral Ice.

Salicylates – Like the salicylates found in many oral pain relievers, these compounds may work by inhibiting prostaglandins. They primarily work topically as counterirritants, themselves stimulating or irritating nerve endings. Brand name examples of topical analgesics containing salicylates include Aspercreme, Ben-Gay, Flexall, Mobisyl and Sportscreme

 

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Moon Yakopatz
25 Aug 2010, 13:20
I have oa, I was scheduled for knee replacement 9/19/08, but because my insurance would not give me a written approval to use this doctor as "in network" I backed out of the operation, I was 52 then, bone on bone,with no acl in that knee.
I was told about gelatin. I started taking a heaping tbs 2 xs a day. Just mixed it in some hot tea in the evenings.
By the end of December that year, about 6-7 weeks later, after having to take the last week of the year off to get rid of vac days ect... I rode horse back all week, lost my phone so ended up walking every where I rode to try and find my phone, the property is very steep and hilly, about 100 acres. By that Wed I realized that I should not be walking at all. That is when I first noticed the gelatin helping. I have taken it every since. I am pain free, I don't limp any more, nor do I live on pain medication to get thru the days and nights.
Gelatin is natural and I recommend it to anyone. It is not a huge investment to see if it will help you. I buy it online, less than $50 for 5 lbs.
just look for unflavored gelatin, hope it helps you
How does it work, you may ask??? Have no idea, but it does for me.
You are worth the investment and 8 weeks of time to see if it helps or not.

mz
Jami
10 Aug 2010, 17:05
Hello I see that I am the youngest cat here. I am 29. I have degenerative disk disease and osteoarthritis of lower back and knees. I have been unable to work for about a year now due to me being in pain most of the time. I am on pain killers and muscle relaxers, but those don't work anymore. In December at 30 years old I am having back surgery-they are putting metal rods in my back in hopes to keep my spine straight. Not looking forward to that!
bernard
24 Jul 2010, 21:49
I have OA for a while. I am fighting knee replacement.
In the next few days I am scheduled for an injection. I hope it will help.
Helen
15 Jul 2010, 08:03
Nan, Georgine, and Suzanne,
I have just been diagnosed with polymyalgia rheumatica. i am 61 and have had two hip replacements due to bone on bone. I have some questions you may know the answer to. I just started the 15mg prednisone for the first month regime. Before being diagnosed by a rheumatologist- I was on 30 mg and then 20 mg. With 15 mg. I can function during the day, but by evening and during the night I am in pain. Is this supposed to be? I want to be on the lowest dosage possible that will work. Also what do we do about exercise and being active. I don't know how much to do- what is best for my body. I also wonder how the steroids work. Do they just take the pain away- so I can function or do they do something to effect a cure- and stop the inflammation.
Thanks so much for any help.
Helen
Elaine
19 Jun 2010, 16:34
My husband has developed OA in his wrists - he is only 53. As driving plays a major part of his job, as well as carrying heavy weights, i am desperate to find something that will help him as he is in a lot of pain.

Any ideas?
Lynette
01 Jun 2010, 16:36
Have had oa for 8 years, was on celebrax, twice caused blood clots in right leg.It was the only thing to date that relieved the pain & stiffness. I just take otc and live with the pain. If you can call this living.
julia haden
18 May 2010, 20:31
im 56 years old found out i have degenertive disk disease 6 years ago very painful. im also bipolar but on meds.iget injections neck shoulders hips epiderals from neck down and bottom up very painful i feel for all of you god bless you all
BILL HENDERSON
15 May 2010, 16:14

I am a 79 year who currently suffers from arthritis in both knees. My R knee is a total replacement, currently causing more pain than the one needing to be replaced! The replaced knee "altered" my hip angle and forced me to have hip replacement "which is now working wonderfully" but find no relief from pain in both knees (new and original) and wondering if anyone has tried Insta Flex?
marjorie
30 Apr 2010, 16:44
I am 43. I have OA in my hip. I'm on 200mg Celebrex. I walk, use the take control with exercise dvd, and changed my diet some. But, still having pain. Am I doing to much. Or is there something else I need to be doing.
Georgine Snyder
21 Apr 2010, 19:15
For Nan Kelly,
I have also been diagnsed with Polymyalgia rheumatica. I am 65 y.o. and have been treating since Nov.2009 with Prednisone. I have been trying to reduce my does but can only get down to 12 mg and I am still quite uncomfortable and cannot walk any distances to speak of. I have been very active , swimming, gardening etc. and don't want to give up. I have decided to try Methotrexate to see if I can get my life back. Please tell me what you are doing to get relief.
manhar
20 Apr 2010, 09:30
my mother is suffering from osteo arthritis.age:48 yrs,so which treatment is best????????
lana t
24 Feb 2010, 20:18
I am a 41 year old lady and been diagnosed with oa in my left knee and believe its all through my body, CAN A MRI DETECT all of my pains i feel? im very stiff when wakening up, after sitting or standing in one position to long, every bone from my toes to my neck crack and ache as well. i need to get tested for all my aches.......which is the best test for me??????
zackie
17 Feb 2010, 07:59
HI all
does anyone have a problem with being unable to queue i.e. at a bus stop or anywhere being unable to stand in one spot haveto walk around and sit down on a fold up stool.
also stretching my legs down is painful in bed tend to sleep curled up in a ball. I cant seem to find out what this is orthopedic
have not helped. nobody tends to believe me
have been trying to get an mri scan this I will have to pay for even if i can get one.all i can say is it came on after intensive ultrasound not done through nhs when i felt
something creeping behind both knees and have been like this for 10 years anyone with this condition any surgeon or trial
interested.anyone out there have this.
greenbudgie
Brandy Mitchell
16 Feb 2010, 15:53
hello everyone... im 22 and just found out that i have oa in the spine, its incredable painful. ive bein heathy other than livin with migrans, severe depression and bi-polor but im on meds for that. can anyone give me advise on how to deal with this and what to do for the pain? god bless you all i will keep all of you in my prayers
Rhonda
11 Feb 2010, 12:38
Hi! I'm new here and have read all the comments. Most people have OA in there hips and knees. I was told 3 years ago that i have it in my hands and that the shots would only work for a while and surgery was not a option for me. Both thumb joints have fused together and the rest of them are working on it. I take motrin everyday and there are day that my hands are swollen and hurt bad.My kids have to open jars, soda or water bottles being i can't anymore. I took the Glucosamine for awhile but it doesn't help, if anybody has any sugestions that would help they would be appreciated.
Rita
11 Feb 2010, 09:18
Dr wants to inject my knee with a Natural medication I could not understand the name but it started with an SIM....... He's doing this because the cortisone shot only lasted a month. Dr said it may or may not work...has anyone ever tried this ...I have OA..
Beverly
10 Feb 2010, 17:02
Hi. I'm new and I have OA and Fibro throughout all of me most severe in my right hip. The Dr. wants to inject me with cotizone shots in the groin first, then an MRI to check for torn ligaments that may be repairable and if that doesn't work then they'll replace my right hip. As if the constant pain isn't enough. My rhumatologist told me these are just steps to the inevetable. A full hip replacement that I need. I'm 57 years. This damage was started 37 years ago in a car accident. Please pray they'll do the hip replacement so the falling and pain will stop. Thanks.
Joyce
08 Feb 2010, 08:02
I woke up one morning is severe pains in both my arms,from shoulders to hands. I have been diagnosed with Osteo-arthritis in both arms, neck,and spine. I have been going to P.T. for the last 2 months,doing stretches,and light weight lifting. I have improved enough to stop P.T. for now, but continue doing the exercises at home every day.So far I only take a tylenol or Advil occasionally. My Rhuematologist prescribed Boniva injections every three months.I have very little pain now. (Pray God!)
Rita Regnault
06 Feb 2010, 20:02
I have OA in wrist, neck, & knee. My knee gives me the most trouble. Had arthroscopic surgery last yr. had torn meniscus. did PT, water exercises & my knee still hurts. I wouldn't call it pain I call it STIFFNESS it's still puffy & have difficulty walking normally. take Etodolac 2 x / day & glusomine chrondrotin. Had Prednisone shot in knee helped for 1 month now it's swollen again... ANYONE ELSE HAD THESE SYMPTOMS ?
Linda
06 Feb 2010, 00:09
To Marie:

If you are in severe pain, you are doing more damage by waiting for the knee surgery. New knees last twenty years now and are the only hope for some of us. I had pain for fifteen years before anyone took me seriously. Then I lost my job/insurance and had to file for Social Security which was approved after a year and Medicare started after one more year. In that two extra years my thigh bones had chewed away the top of the lower leg bones. If I stopped walking I had to literally pull my upper body out of the lower part of my legs. I spent roughly 3 years of my life all but bed-ridden. Finally, my surgeon said "Where have you been and what took you so long to get here? We'll schedule your surgery for next week!" That man saved my life, my sanity and greatly improved my mobility! If everything else worked as well as my knees, I would have no complaints.

To make a long story short; I have learned from over surgical patients, that the ones that look forward to "owning" a new set of knees recover very well and very quickly; whereas, the ones fearing the surgery or not really on board about the surgery DO NOT do as well by a long shot. After my knee surgeries I felt so much better that I did not even take ANY pain medication. After living with the pain for so long, the surgery was like a walk in the park. I know my case (and pain tolerance) may not be the same for everyone else; but, knees replaced by a reputable surgeon can change a persons life. I wish all of you could be so fortunate as to have my surgeon and my outcome!!! Wish you well!
Irene Sprague
05 Feb 2010, 09:38
Have Advanced Osteoarthritis and had a total right hip replacement in '07 at the age of 43. Saw a dr that treats athletes and when I couldn't walk without crying he finally agreed to do the surgery. It was an excrutiating recovery for the first 3 weeks but its been a life-saver and I recommend EVERYONE get joint replacement. I currently am going into surgery for left shoulder pain that with an MRI was diagnosed as C6-7 fracture of the vertebra and a herniated disc all related to degenerative joint disease. My bone dr said he didn't recommend the chondroitin he feels it doesnt really work. No other drugs were given to me either.
Marie
04 Feb 2010, 20:02
Hello, Iam new here but I have severe OA in my knees. I to need surgery to replace both knees. I suffer with severe pain all the time. I take two kinds of pain medications and diclofenac twice a day. I need surgery but like others I am afraid of the surgery. Can anyone tell me how much more pain is involved in knee surgery. Hoping all of you a better day.

Phyllis
03 Feb 2010, 17:54
I am 59 and just had a total knee replacement, which I had it done a couple years ago, now I need left knee done hardly can wait, I am in a lot of pain all the time, I hae fibro and OA also its no fun.
suzanne
03 Feb 2010, 10:36
For Nan Kelly

I have had polymyalgia for years. Usually it does not last longer than 5 years but there is no specific time. Prednisone is the miracle drug that allowed me use of my arms when I was first diagnosed. It was trulu like magic. It also now helps with my OA and RA. God luck.
Dawn Harris
03 Feb 2010, 09:33
Dear Sandy1
I feel for you. I am only 41 years old, but have a lot of the same pains as you. I live in Atlanta, GA and go to a great doctor. He is a pain relief doctor and he does pain blocks on me. His name is Dr. Randy Rizor 404-816-3000. I have had lumbar blocks done to relieve the pain in my legs, feet, knees, and ankles. I have also had blocks to relieve the pain in my arms, elbows, and wrists. If you don't live in or near Atlanta, try to find a doctor near you that will at least try doing one of these blocks on you. I think you will be pleased by the results.
betty kosegi
03 Feb 2010, 04:01
I've had operations on both knees for torn cartilage but they continued giving pain.I found out it was Arthritis doing it so got Gel Shots,five in each knee but pain continues.My Dr. says to go as long as I could then I will need Knee Replacements.I'm worried about it as I have a cat and don't have anyone to help me out.
Linda
02 Feb 2010, 22:52
I was reading this article and wish there was some way to get Bextra back on the market. I have osteoarthritis all through my body and am so frustrated because the Bextra worked for me. I'm alllergic to seafood so can't take the glucosamine and chondroitin. I'm taking pain pills every day to get through the days. I have had 2 spinal operations and just had my second rotator cuff becasue the spurs from the arthritis shreeded my rotator cuff muscles.
Nan Kelley
02 Feb 2010, 21:08
I have been diagnosed with polymyalgia rheumatica

Does anyone suffer from the same?
tonie
02 Feb 2010, 16:58
sandy1:
find a good Rheumatologist in your area who handles FMS. I have the one who diagnosed me, he is so good. You have to find out if they work with FMS patients beforehand. Some of them don't.
Jerme, God will indeed hear your prayer. Just keep on praying. That is what I do every morning, I pray for strength to get thru the day. God BLess I will pray for you
Tonie
Sandy1
02 Feb 2010, 13:32
Hello,

Iam 65 years old,been diagnosed with fibromyalgia,Chronic Fatique,Degenerative disc dease,and O.A.in my feet,they have bscme deformed and sooo painfuf, inmy knees in my hips,in my back, shoulders,elbows wrists,and hands.I've had Disc surgery and foot surgery. I take 12 drugs daily and still don't feel good.Is there any kind of doctor who handles all this at once? Don't like to take pain meds etc.

Thanks,

Sandy
elisabeth Micalizzi
02 Feb 2010, 13:02
I also need a Knee Replacement, I am afraid, I am tired of being in Pain. God give me Strenght. Taking Celebrex, all these Medications are not good. Oh well, thats the Golden Years, ha ha ha
ruth mckenney
02 Feb 2010, 10:31
KaTay, I do phys. therapy in the form of Rolfing once per wk atta cost of 50$ per throw. It is painful, but it has enabled me to walk, to do my own housework, to act without AS MUCH pain.........and I take Hydrocdone 660 four times per day. What a relief! Talk to you physician? I am now in my 75th yr. and have suffered since I was 65.
Pamela C.
02 Feb 2010, 10:31
I was diagnosed with OA 2 years ago, severe in my knees, had a total knee replacement on the left in November and I am thrilled with it. I am 52 years old and should have had this surgery done at least 6 years ago. I am now getting ready to start the process to get my right knee replaced. I do take Hydrocodone at least on a once a day basis, just to keep the other knee from driving me outta my mind until it's done. I can finally walk without severe pain in the left knee with every step for the first time in YEARS, and I only use a cane if I am walking long distances. Don't wait to long for replacement surgery if you ask me.
Nickie
02 Feb 2010, 10:29
Diagnosed with OA in 2008. I have Valgus knee deformity, no cartilage and large bone spurs, and bone chips. Also my knee caps are not where they are suppose to be, they are shifted. Dr. said I am too young for knee replacement, I am 36 now. Left knee is so bad now, I can hardly bend it. Right knee is getting worse for compensating for the left.
Any help or hope or info. would be greatly appreciated. Had injections, but they only lasted 4 months, now I have NO insurance, so I have little hope for help.
katie
02 Feb 2010, 10:26
I have osteo in jaw(tmj),spine(including neck), hips,knees, r big toe-basically every joint weight bearing-my elbows wrists are fine and fingers. My alignment is very bad cause of a curve in my spine that was not managed well. I've never found a med that works well-diclofenic gave me headaches. what has helped are custom orthotics that put my feet in a neutral position(not overcorrecting), even took away some neck and jaw/face pain which was great relief-also no more pain in big toe. I also get help from massage and do stretches that don't twist. My physical therapist (my fourth)is great, others made things worse-bad listeners-bad skills. I'm seeing a rheumotoligist in may and looking forward to it-he is 3 hours away as we live in a rural area and have limited choices. Like all of you, I'm searching always for a new technique, something, trying not to give up. I would like to try water therapy when weather gets nice. God Bless you all!
geminipat
02 Feb 2010, 09:39
I am 62 years of age and have had both hips replaced. It was the best thing that ever happened to me. All of the hip pain is gone. I was walking with two canes just to get around. Had the first hip done in 2007 and when I started having the same pain in the second hip there was no question about the surgery. What a relief! I am an aquatics fitness instructor and the water does help with the pain in my knees and back. I have three herniated disks in my lower back and was told that as long as I keep up the water fitness there will be no surgery. Fantastic!
Ka-Tay
02 Feb 2010, 09:29
I was diagnosed with OA over a year ago. Also have spondylothesis. Fell when I was about 8 on icy step, fractured both sides of L5, which was displaced. Affected both S1 & L4. C4-5-6 &7 affected by OA as well as S1, L4 &5. OA in both hands. Difficulty holding &maintaining things in right (dominant) hand. Pinky, ring finger &thumb on right most problematic. Took Glucosamine &Chondroitin for over 10 years. I am 55 now ¬hing I take seems to help. Quit taking Gluco/Chon as was told affects my diabetes. Unable to sit/stand/walk for extended periods now, affecting concentration. No longer able to concentrate as pain constant. Aquatics &hot tub helps, but can't afford the fee for gym any more as unable to work. Any suggestions? I'm at a loss now.
Rosalie
02 Feb 2010, 09:23
Diclofinac, as I understand it, has to be used carefully. I also was taking this twice a day for inflammation in my fingers-- very painful -- and it did help. There is a long term risk of liver damage, so this should be used prudently, and not 2xday 365 days a year for many years, as the risk increases.
Jerry
25 Jan 2010, 23:05
After hearing of and asking my Dr. about glucosomine-chondroitin with msm I did research and finally began using a brand. (The product is not FDA approved so your Dr. cannot recommend it but he/she may give you some information.)
After about three weeks of use I felt improvement and stopped taking the prescription medication I was on. I stopped limping!! It has served me well for the past few years.
Jerry
xtopher
15 Jan 2010, 12:01
hi, i had pains on my anckle, initially i never knew anything about OA until i took an x-ray and the doctor told me i have OA.

i have taken a lot of pain relief but the pain persist.
i work in a factory and i am always busy.
eachday i close work, i feel great pain.

what do i do? stop work?
it has affected my hip joint and knee.

the doctor told me the only alternative is surgry. what about food supplement? is there no other remedy?

Canuck
05 Jan 2010, 19:26
I have OA & the best relief for me is water
exercises, stretching & light weight lifting. I also take Glucosamine/Chondroitin
& MSN.
Alternating periods of Exercise & Rest can be helpful.
God bless you all!
janet snow
17 Dec 2009, 20:02
i just had total hip replacement @ 51 yrs of age. i am SO relieved. i was on crutches for 2 months prior to my surgery because i was in so much pain. the 35 yr old above needs to push to get her hip done now. they last 20 years, and at 55, she will still be young enough to recover quickly from the surgery. it is NOT worth being in pain to prove you need a hip replacement. DO IT, you take the lead, it is your body. i would do it again as i am soooo relieved of pain. going on 2 weeks since my surgery. good luck to all.
Eve
17 Nov 2009, 10:18
I am new to the forum. I am 63, I have had R.A. for 4 years, I feel as though I have had it longer, but was not found earler. was told 3 mo. ago that I also have OA. I take Methotrexate, Enbrel Shots and Actonel, once a week, it helps quite a bit. I get a little stiff when the weather gets cool and damp.
But I keep moving, thanks to my hubby and dog.
Wishing you all happy days and better movement.
TheSpirit
11 Nov 2009, 16:56
Hi,
I have Hallux Rigidus (OA in the big toe joint) I am scheduled to have surgery (Cheilectomy) in a month, has anyone else had this treatment and what was it like regarding post op pain and recovery

Thanks
sissy helms
03 Nov 2009, 09:48
I have been in pain for server years & I take Morphine & Hydrocodone 3 to 4 times a day. I dont get full releave & I have to push myself every day just to get out of bed. I am not a person to lay or sit around & i cant work so I dont have money for a lot of new medicine. I would like to know what is out there for me. I have tried all the over the counter drugs & nothing works.
HELP!!!
everett
07 Sep 2009, 20:55
I have a Electroplasma device produce PEMF
Pulse Electromagnetic field with frequency around 4 to 21 pulses per second, after 30 minutes the paint gone 30 to 40% just the first time after 8 session of 30 min. the paint relieves is 90 to 100%.
working together with Glucosamine hcl msm and flex with these kind of products working better, with treatment of just 30 days regenerate cartilage bone and fiber
How it does ? is simple the electro-pulse make the cellular generate oxide and calcium.
Debby Griffin
05 Sep 2009, 17:44
Why isn't the anti-inflamatory drug, DICLOFENAC mentioned above? I take two a day and the OA is under control.
jerme paul lumen
30 Jul 2009, 21:56
hi!... im 21 yrs of age i got a OA this started when im 19 i got a sever pain but i experience. hope god hear my prayer!!!
Theresa McGuinn
13 May 2009, 08:17
hello to all, for Katherine B,i am sorry to hear that you have OA in both hips from hip dysplasia which you've had all your life, i am 35 and also have hip dysplasia and OA in my hip,last july i had an arthroscopy but all this did was to straighten me up as my posture was suffering, i am in alot of pain everyday and take alot of drugs to help my pain, i am very active as i work in a primary school and we always seem to be out walking somwhere or at some activity, because of my age they will not give me a hip replacement untill i get a little older or i really cant stand the pain anymore, my question to Katherine is what do you take for pain relief?
Mary
24 Apr 2009, 12:03
What form of Athritis is spondlyosis?
Sylvia Smith
16 Apr 2009, 11:00
I have it in my right hip, I am on no drugs, but I also have RA and I am on drugs for that.
My doctor hasn't told me what to take for OA, so I just take the pain when it comes. I don't have that much pain, it depends on the weather.
One day I may have to have hip Surgery, but I am not rushing it.
It their any books on it, like what exercires I can do.

Thank you
SEARRYIFUFAMS
18 Mar 2009, 12:27
Hi there!

I'm just new here - saying hello! :)

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