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Conditions > More Conditions > Restless Legs Syndrome Doubles Risk of Stroke and Heart Disease
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Restless Legs Syndrome Doubles Risk of Stroke and Heart Disease

People with restless legs syndrome are twice as likely to have a stroke or heart disease compared with people without the condition, and the risk is greatest among those with the most frequent and severe symptoms, according to the largest restless legs syndrome study to date.

The study involved 3,433 men and women enrolled in the Sleep Heart Health Study, a large prospective cohort study of adults age 40 and older designed to investigate obstructive sleep apnea and other sleep-disordered breathing as risk factors for the development of cardiovascular disease. Participants were diagnosed with restless legs syndrome by detailed questionnaire and were asked if they had been diagnosed with a variety of systemic diseases including cardiovascular disease and cerebrovascular disease. Of the participants, nearly seven percent of women and three percent of men had restless legs syndrome.

Restless legs syndrome is a neurological condition characterized by the irresistible urge to move the legs, particularly when at rest.  Although the relationship is unclear, restless legs syndrome is often associated with fibromyalgia and some other forms of arthritis and related conditions. 

The new restless legs syndrome study does not show that the condition causes cardiovascular and cerebrovascular disease, but a number of potential mechanics for such a process exist, says study author John W. Winkelman, MD, PhD, of Harvard Medical School. “In particular, most people with RLS have as many as 200 to 300 periodic leg movements per night of sleep and these leg movements are associated with substantial acute increases in both blood pressure and heart rate, which may, over the long term, produce cardiovascular or cerebrovascular disease.”

Dr. Winkelman says there are limitations to the restless legs syndrome study, including that the diagnosis was self-reported via questionnaire rather than by clinical interview. The study was published in Neurology.

diane c.
27 Apr 2012, 18:44
I have RLS too & I use Requipt which helps tremendously! I'm also on prescrition pain killer & muscle relaxers for my cronic pain from lower back surgury & right knee repacement 2 yrs ago. I know they also help my RLS. it usually is worse after being on my feet awhile & then when I finally sit down or lye down, it will flare up, in one or the other legs! If I remember, it's better 2 take a requip 30 min before sitting or lying down. Putassium is supposed to help too. I'm also being treated for irreregular heart beat & conjestive heart failure. The heart issues stated about 10 years after the RLS. My grandmother also had RLS! My dad & mom had heart problems too! Guess it's all in the family! I'm 58 yrs old. My left ankle is really bad too! So it can be very painful when the RLS starts up in either leg. Sometimes I'll get up & do something untill the medications kick in, about 30 min. later!
Kathy
14 Apr 2012, 21:26
I have had RLS since about 15 years of age and have used many medications over the past 40 years. Mirapex and Requip have been the best resolution, but the symptoms are starting earlier in the afternoon now. I have to take a half dose about mid afternoon, then a full dose at bedtime. Usually some Tylenol or Tylenol 3 to completely settle it down. I was recently diagnosed with RA and also have significant OA with both knees replaced.
Shelby
03 Apr 2012, 01:18
My RLS is most definately in the "Severe" catagory. Mirapex saved my sanity, but Ive been told by the pharmacist that my next dose increase will put me at the highest dose available with any theraputic value. Since RLS is a progressive condition, what happens when the TLS out-progresses my meds? Im scared.
David Wester
10 Feb 2012, 05:14
My severe RLS has successfully been treated with Mirapex and pain medication.
Pauline
17 Nov 2011, 13:27
I find that a magnesium supplement or Calcium Magnesium mix works for restless legs.

Heat definately makes things worse - I really suffered when I lived abroad. Now, if I feel it starting at night, I stick my feet out the blanket, or onto a cool area of the bed and that usually settles things down!
javaid
29 Sep 2011, 06:17
i have soaring pain from my knees to foot.When i wake up in the morning when i ground my feet on ground it is so painful.i tried lot of medicines but all in vain. is there any remedy other than prescribing medicine.
Joyce Wittschen
22 Aug 2011, 08:56
Dear Joan,

I too, have RLS, and do take Requip, otherwise is wouldn't even get a few hrs. of sleep. I also am a SLP (speech-language pathologist) who has worked for years in the field of children with sensory deficits.

So another suggestion that I sometimes have used when medication alsone has not; is to place heavy blankets, quilts, ets. something with weight to be laid over your lower extremeties to provide some pressure. Not quite sure why the sensory imput helps but oftentimes it has worked for me. It's worth a try.

Sincerely,

Joyce
Joan
05 Jul 2011, 14:44
I, too have Restless Leg Syndrome. It drives me nuts at night, usually about an hour after I lay down. It is intermittent and I don't know what helps. Anyone out there have any suggestions, other than prescription drugs? I tried Magnesium - didn't help.

Thanks.
Sandra Moore
10 Jun 2011, 13:43
Please tell me there is something to releive the jumping, aching, anoying, missery, of ressless legs!!!!!!!! I fing it very difficult to get to sleep befor 3 or 4 in the morning.
maureen
10 Apr 2011, 00:52
sine i have took a sleep disorder test,I found out that I have restless leg problem....BUT my fenmer and leg, and knee sometimes hurt so bad that it feels like it is in the bone. this hurts so bad in the day time, I have trouble walking....it is in my left leg. what gives...?

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