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Keeping Hands in Working Order

Arthritis Foundation-funded researcher seeks better treatment for osteoarthritis at the base of the thumb

By Jeanne Erdmann

Hear the word “arthritis” and you may automatically think of hips or knees. Osteoarthritis (OA) at the base of the thumb is just as common, but has not been studied as much. In fact, when Lisa Mandl, MD, MPH, a rheumatologist at Hospital for Special Surgery in New York City, first started seeing patients in the clinic, she was surprised at the number of people - mostly older women - who came to her complaining of severe pain at the base of the thumb.

Even though the patients had sought relief from cortisone injections, splints, physical therapy and non-steroidal anti-inflammatory medications, they were still experiencing pain severe enough to wake them at night. The only option left was surgical repair of the joint, an option most of Dr. Mandl’s patients were not ready to accept. 

“Hand OA is, to some extent, overlooked because we don’t walk on our hands,” says Jeffrey Katz, MD, professor of Medicine and Orthopedic Surgery at Brigham and Women's Hospital, one of Dr. Mandl’s longtime mentors.

Although knee and hip OA can literally knock people off their feet, the disability from hand problems is “more subtle but it’s very striking,” says Dr. Katz.

Dr. Mandl says she has seen patients who are otherwise healthy, but their terrible thumb pain is ruining their lives.  “It struck me how they’d waited to retire and play with the grandkids, and then couldn’t do it.”

Dr. Mandl set out to learn everything she could about carpometacarpal OA. She read everything in the medical literature only to learn that not much is known about this type of arthritis.

The carpometacarpal (CMC) joint is at the base of the thumb, where the thumb attaches to the hand. Like arthritis in the hip or knee, the pain comes when the cartilage wears away so much that bone rubs against bone. As with OA of the knee and hip, CMC OA is more common in women than men. By age 80, up to 80 percent of women are affected.

CMC OA interferes with daily activities in kitchen, around house, in people who do keyboard work, or assembly work or need to use power tools.

Dr. Katz expects the prevalence of hand OA to only worsen as the older population stays more active and stays in the workplace longer. “It’s one of those older worker problems,” he explains. “As the workplace ages, we need to develop work tasks and equipment with the understanding that more workers will have this problem.”

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Franko
31 Dec 2011, 02:03
I concur with MD Reichman as to the benefits of Diclofenac (Voltaren) gel. As a Rph, I hear a lot of feedback from many MD's and fellow Rph's and as a sufferer of AS, I have found the Voltaren gel to be effective for feet and hand arthritis pain and joint stiffness.
Mandy
10 Nov 2011, 11:29
I've recently started therapy with an occupational therapist who specializes in hand. She has made a brace for each thumb from something like friendly plastic that fastens with velcro. It is helpful in holding the steering wheel when I drvie, fastening seatbelt, opening heavy doors, and working with various equipment in the gym.
Charlotte Hamilton
26 Oct 2011, 23:01
I too suffered with the excruciating pain at the base of my thumbs. I am 58 years old. I was referred to a rheumatoligist for this and other OA symptoms. He has been a total god send. He put me on an herbal supplement which is a natural eggshell membrane it is called Jointhealth and made by a company called Membrell. As long as I take this I do not have the pain and discomfort in my hands and knees. The Arthritis Foundation should do a study on this product. Please consider this information - it could be so beneficial to many other people who suffer like I used too!!
Sally
17 Oct 2011, 20:44
I'm only 40 and already have OA in my thumb joint!!! I find it funny you talk about this as if only old people are affected.
Pamela Corney
15 Oct 2011, 14:54
I'm an active, healthy 54 year old fitness instructor and competitive athlete. I've been looking for a good hand surgeon in the Metro Detroit area for my carpometacarpal OA. I know I can research UofM, and I will, but I am wondering if any one of you might know of and are able to recommend someone you have heard of or know. I would really appreciate any information on hand surgeons in MI. Thank you! ~Pamela
Gloria Wessely
12 Oct 2011, 18:21
I have had a total hip replacement and within the past two years have discovered that my cartilage is wearing away on my R thumb and is near bone and bone. For two years in a row I have received injections at the site from a Hand Surgeon. I also have an Arthritis glove that I wear as I type about 7 hours/day for 5 days/week. The thumb bothers me immensely after cleaning as well - especially vacumming and scrubbing.
Tami Logue
12 Oct 2011, 18:12
I had thumb surgery using one of the tendons from my wrist. My thumb works terrific but the surgery caused trigger finger in my middle and ring fingers. Dr. did another surgery to release the trigger finger which caused my middle finger to hyperextend. A further surgery allows me straighten my finger most of the way, but I have no grip and a lot of pain. I take gabapentin for the pain but it doesn't help much. I would appreciate any suggestions. Thank you.
Rebecca
12 Oct 2011, 16:26
I have spent many years doing hand sewing/embroidery and had carpal tunnel surgery years ago, but arthritis is now my biggest nemesis. I use Voltaren gel and find relief in addition to using a heated mit, but not at the same time as the gel. I am able to do more hand sewing now, but not as much as I wished.
Ronald Reichman MD
12 Oct 2011, 14:16
As a Rheumatologist, the incidence of thumb (1st CMC joint arthritis) has long been known as the most common site for osteoarthritis, and can be debilitating.

I have had great success using topical NSAIDs as a much less invasive (and more frequently successful) treatment.

The FDA has approved 2 topical NSAIDs for Osteoarthritis (PenNSAID and Voltaren Gel), although the primary indication is for knee osteoarthritis.

The local delivery of NSAIDs (which we Rheumatologists have been using for many years by having these compounded) offers the advantage of significant local relief with a dramatically reduced plasma level(1/100th) of the drugs (thus theoretically reducing the potential risks of NSAIDs).
Marianne Goodwim
12 Oct 2011, 12:15
I have had surgery on both thumbs. The first one I had the tendon interposition arthroplasy--that one is great. After reading about the artelon implant I asked my surgeon if he could do that. He said he had never done that but had done a procedure using graft jacket while doing his fellowship. I had this procedure done with the graft jacket. It is nowhere near as good as the first--and my thumb is still very painful--not as much at the CMC joint, but at the hyperextended MP joint. I want a revision done with some kind of procedure to tighten up the hyperextended joint--just trying to decide when.
Joan E
12 Oct 2011, 11:17
I too chose the surgical option on both thumbs and feel like I have my life back! I couldn't even use a can opener or hold a paper plate with my hands. This option may seem drastic to many but I have already had 2 total knee replacements so it was easy in comparison! At the age of 50 I was not willing to give up on life easily!!! I am so grateful I found the perfect hand surgeon and had the will to want to be proactive in my rehab~ Attitude is everything!!!
Judy
12 Oct 2011, 11:15
I am a 54 year old woman, and I have Bouchard Nodes on eight of my knuckles and hard knots in the palm of my hands. Both thumbs have had two cortisone shots each within the past two years. I have trigger fingers at times. What time of supplements will help?
Thank you and God bless,
Judy
Margaret Skrod
12 Oct 2011, 10:10
Thank you for addressing this very painful form of arthritis. I thought I was one of the few with arthritic hand and thumb pain. I have been fighting this disease in other parts of my body as well and have had the knee injections which helped. I attend the gym 5-6xweek in order to stay active and keep the arthritis at bay but recently I'm finding that I can hardly lift the free weights due to severe hand and thumb pain. After reading this article, I have hope that I will have complete use of my hands again.
Janice J
12 Oct 2011, 09:04
Personally I don't know why anyone would no accept the surgical replacements since they finally have them available. I had my right thumb done in 2008 and the left in 2009 and its amazing to be pain free and have total use of my hands where before I couldn't even hold a pen and write any more. If they can slow the process down, great, but there's no reason to suffer with it if you don't have to any more.
Cindy Olson
05 Oct 2011, 09:20
Thank you to the doctor for recognizing this 'silent' osteoarthritis condition. Thank you to the reporter for bringing Dr. Mandl's work to our attention.

The pain is excruciating, and it's just a wonder to me that it's never mentioned in the general information available on the web. As Dr. Katz said "it's overlooked because we don't walk on our hands" -- but likewise, we don't surf the web (or even the tv) or type or text with our hips or knees! It's time the digits got their due!!

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