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Drug Class:

Biologics (Other)

Brand Names

Prolia, Xgeva



60 mg given by injection every 6 months.

Potential Side Effects


Back pain; bladder infection; high cholesterol; muscle pain; pain in arms and legs.

Special Instructions

  • Take at least 1,000 mg calcium and 400 IU vitamin D daily.
  • Injection should be given by a health care provider.

Be Aware

  • Tell your doctor if you cannot take daily calcium and vitamin D, have had parathyroid or thyroid surgery, plan to have dental surgery or have low blood calcium, kidney disease or trouble absorbing minerals.

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

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