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Drug Class:

Uric acid drugs (Xanthine oxidase inhibitor)

Brand Names




100 to 800 mg daily. Your doctor may adjust your dose so that your blood uric acid level is lower than 6 mg/dL.

Potential Side Effects


Gout flares; hives; itching; rash.

Special Instructions

  • Never start or stop this drug during a flare.
  • Stop taking medication at the first sign of a rash, which may be a sign of an allergic reaction.
  • Take immediately after a meal.

Be Aware

  • Before taking allopurinol, tell your doctor if you use azathioprine (Imuran) or if you have kidney disease. Gout attacks are common when this drug is started. These attacks can be reduced by taking lower doses and by taking the drug with colchicine or NSAIDs.

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

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